Fats and Testosterone: Dietary Fat, PUFA, & Androgens

By Ali Kuoppala | Last reviewed Mon 24 September 2018

Medical Review by Dr. Vlad Belghiru, MD

Nutrition has a key role in our natural testosterone production. And one of the biggest factors in our diets is macronutrient ratios and the types of macronutrients we consume.

When it comes to dietary fat, it has arguably the largest impact and room for manipulation. Increasing or decreasing the total intake of dietary fat as well as focusing on the different fatty-acids and their ratios can move your rate of testosterone production up or down quite drastically.

This is also a topic that creates a lot of confusion. All kinds of experts are telling people to “just eat more fat” and “increase their intake of healthy fats”, but really, with the healthy fat they often refer to the unhealthiest kind from a hormonal perspective.

The Impact of Dietary Fat on Testosterone Production

testosterone and dietary fat intakeAll steroid hormones have a structural backbone of a 17-carbon fat molecule called “gonane”, this makes them fat-soluble hormones.

Because of this, it’s only natural to assume that increased amount of dietary fat, could lead to improved production of steroid hormones.

And according to research, it does, but there’s a caveat, which well be getting to more in detail below.

First however, let’s take a look at the different fatty-acids we consume:

  • Saturated fatty-acids (SFAs) are hard in room-temperature and contain only single bonds between the carbon atoms (butter, coconut oil, lard, cacao butter, palm oil, red meat, dairy products).
  • Monounsaturated fatty-acids (MUFAs) are liquid in room-temperature and contain one double carbon-carbon bond in the structure with rest being single bonds (olive oil, argan oil, avocado).
  • Polyunsaturated fatty-acids (PUFAs) are liquid in room-temperature but contain multiple double carbon-carbon bonds (soybean oil, canola oil, sunflower seed oil, cottonseed oil, fish, margarine, etc).

Now, if we start to look at the research, we can see that the same pattern takes place in majority of the studies; total intake of mixed fatty-acids results in increased testosterone production, increased intake of SFA and MUFA results in higher testosterone production, BUT increased intake of PUFA suppresses testosterone production.

Good example of this is a human study by Volek et al.1, which found out that total fat intake, SFA, and MUFA raised serum test levels, but when the ratio of PUFA to SFA was increased, testosterone production took a nosedive.

fatty acids and testosterone

A Finnish study by Hämäläinen et al.2 is also a prime example of the importance of total fat intake. The researchers made their subjects switch from a diet containing 40% calories fat (mainly from animal sources) into a diet that contained 20% calories from fat (mainly from PUFA), and then back again into the 40% fat. They found that testosterone levels plummeted when the subject switched to the low-fat diet, and returned back higher when the fat intake was lifted back to 40%. Another human study by Bélanger et al. did similar change and saw similar results, switching to lowered fat intake (and higher PUFA) resulted in significantly lower levels of androgens3.

different types of fatty acids and serum testosterone levels

This may explain why vegan men tend to have slightly lower testosterone levels in majority of the studies, as their diets are quite low in fat, and the fat they get comes mostly from PUFAs, what also seems to occur in all of these studies is that lower SFA higher PUFA results in higher SHBG and less testosterone bioavailibity.4–6

So more fat, more testosterone?

Not necessarily. There seems to be a point of diminished returns, and this is simply because you also need to leave some room for carbohydrates and protein. For example, one study with hockey players dropped fat intake from 40% to 30% while simultaneously increasing carbohydrate intake from 45% to 55%, this resulted in elevated testosterone levels7, not something you’d expect by looking at the evidence above.

What makes PUFA so bad and how much total fat should I eat then?

The reason why polyunsaturated fatty-acids suppress testosterone and thyroid hormones is likely caused by the fact that they have the long sensitive carbon-carbon chains in their structure. This makes the fatty-acids very unstable when in contact with oxygen, heat, and light, causing them to literally go rancid inside the body through a process called “lipid peroxidation”. This creating free radicals and eventually oxidative damage in the cells8.

So if you’re trying to figure out the optimal intake of dietary fat for testosterone production. It likely falls between 25-40% of your daily calories. What should be the determinator is your intake of PUFA. If you can minimize polyunsaturated fat consumption, you may go as low as 25% fat and keep your testosterone production churning. However, if you do eat some PUFAs, it’s better to consume slightly more total calories from fat, more like 30-40%. In either case, I wouldn’t recommend going over that since you also need to leave room for carbohydrates and protein (which both have their role in the production of androgens).

Conclusion on Fatty-Acids and Testosterone

There are some pretty clear conclusions to be drawn from the studies above, such as…

  • SFA and MUFA are great for testosterone production.
  • Total intake of fat should land between 25-40% daily calories.
  • Increased intake of PUFA suppresses testosterone, likely due to lipid peroxidation.


References

1.
Volek J, Kramer W. Testosterone and cortisol in relationship to dietary nutrients and resistance exercise. Journal of Applied Physiology. http://jap.physiology.org/content/82/1/49. Accessed February 12, 2017.
2.
Hämäläinen E, Adlercreutz H, Puska P, Pietinen P. Diet and serum sex hormones in healthy men. J Steroid Biochem. 1984;20(1):459-464. [PubMed]
3.
Bélanger A, Locong A, Noel C, et al. Influence of diet on plasma steroids and sex hormone-binding globulin levels in adult men. J Steroid Biochem. 1989;32(6):829-833. [PubMed]
4.
Hill P, Wynder E. Effect of a vegetarian diet and dexamethasone on plasma prolactin, testosterone and dehydroepiandrosterone in men and women. Cancer Lett. 1979;7(5):273-282. [PubMed]
5.
Howie B, Shultz T. Dietary and hormonal interrelationships among vegetarian Seventh-Day Adventists and nonvegetarian men. Am J Clin Nutr. 1985;42(1):127-134. [PubMed]
6.
Key T, Roe L, Thorogood M, Moore J, Clark G, Wang D. Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores. Br J Nutr. 1990;64(1):111-119. [PubMed]
7.
Tegelman R, Aberg T, Pousette A, Carlström K. Effects of a diet regimen on pituitary and steroid hormones in male ice hockey players. Int J Sports Med. 1992;13(5):424-430. [PubMed]
8.
Mylonas C, Kouretas D. Lipid peroxidation and tissue damage. In Vivo. 1999;13(3):295-309. [PubMed]
Fats and Testosterone: Dietary Fat, PUFA, & Androgens was last modified: October 15th, 2018 by Ali Kuoppala